List Of Pathological Bodies
- Negri bodies (intracytoplasmic) – These are eosinophilic cytoplasmic inclusions that are characteristic of neurons infected with the rabies virus.
- Guarnieri bodies (acidophilic intracytoplasmic) – These are dense, round, and acidophilic inclusions that are seen in cells infected with the smallpox virus.
- Owls bodies (intra-nuclear and cytoplasmic) – These are intranuclear and cytoplasmic inclusions that are seen in cells infected with cytomegalovirus (CMV). They are called "Owls" due to their resemblance to the eyes of an owl.
- Cowdry bodies (intranuclear) – These are eosinophilic intranuclear inclusions that are seen in cells infected with herpes simplex virus (HSV) and measles virus.
- Downey type II – These are reactive lymphocytes that are seen in patients with Epstein-Barr virus (EBV) infection. They are characterized by their large size, abundant cytoplasm, and irregular nuclei.
- Lewy bodies – These are eosinophilic cytoplasmic inclusions that are seen in the substantia nigra of patients with Parkinson's disease. They are composed of alpha-synuclein protein.
- Zebra bodies (lysosomal) – These are lysosomal inclusions that are seen in cells of patients with Niemann-Pick disease. They are called "Zebra bodies" due to their characteristic striped appearance.
- Councilman bodies – These are eosinophilic bodies that are seen in patients with hepatitis. They are thought to represent dying hepatocytes.
- Psammoma bodies – These are concentrically laminated calcified structures that are seen in meningioma, papillary carcinoma of the thyroid, and ovarian cystadenoma.
- Call-Exner bodies – These are small, round eosinophilic structures that are seen in granulosa cell tumors. They are composed of estrogen-producing cells.
- Loose bodies – These are small, mobile fragments of cartilage or bone that are seen in patients with osteoarthritis.
- Russell and Dutcher bodies – These are large intranuclear inclusions that are seen in cells of patients with lymphoplasmacytic lymphoma.
- Schiller-Duval bodies – These are small glomerulus-like structures that are seen in cells of patients with testicular yolk sac tumors. They are composed of neoplastic cells and capillaries.
- Verocay bodies – These are elongated eosinophilic structures that are seen in schwannomas. They are composed of interdigitating cell processes.
- Hürthle cells – These are large eosinophilic cells that are seen in Hashimoto's thyroiditis. They are characterized by their abundant cytoplasm and large nuclei.
- Hirano bodies – seen in patients with Alzheimer's disease, these are eosinophilic, rod-shaped bodies found in the hippocampus and cerebral cortex.
- Ferruginous bodies – seen in patients exposed to asbestos, these are iron-coated asbestos fibers that are engulfed by macrophages and can lead to tissue damage and inflammation.
- Schaumann bodies – seen in patients with sarcoidosis, these are small, laminated, calcium-containing bodies found in granulomas.
- Asteroid bodies (satellite giant cells, cytoplasmic inclusions) – seen in patients with sarcoidosis, these are star-shaped, eosinophilic bodies surrounded by multinucleated giant cells.
- Mallory bodies (cytoskeletal intermediate filaments) – seen in patients with alcoholic hepatitis, these are abnormal protein aggregates composed of cytoskeletal intermediate filaments.
- Howell-Jolly bodies (remnants of nuclear chromatin) – seen in patients with severe anemia or post-splenectomy, these are basophilic remnants of nuclear chromatin that are usually removed by the spleen.
- Pappenheimer bodies (composed of iron) – seen in patients post-splenectomy, these are small, iron-containing granules found in red blood cells.
- Heinz bodies (denatured Hb) – seen in patients with G6PD deficiency and alpha-thalassemia (HbH disease), these are inclusions in red blood cells composed of denatured hemoglobin.
- Döhle bodies (aggregates of RER) – seen in patients with leukocytosis, these are small, blue-grey inclusions found in the cytoplasm of neutrophils..